产品货号：
Z34153
中文名称：
C-MYC/MYC抗体
英文名称：
Anti-C-MYC/MYC Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-C-MYC/MYC Antibody |
| 指标别名 | bHLHe39;c Myc;c-Myc;MRTL;MYC;Myc proto oncogene protein;Proto oncogene c Myc;Transcription factor p64 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF,IP,FCM |
| 基因名称 | MYC |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human c-Myc Transcription factor that binds DNA in a non-specific manner,yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'.Activates the transcription of growth-related genes.Myc a proto-oncogenic transcription factor that plays a role in cell proliferation,apoptosis and in the development of human tumors..Seems to activate the transcription of growth-related genes. |
| 实际分子量 | 57KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | C-Myc is an oncogene that functions both in the stimulation of cell proliferation and in apoptosis.c-Myc elicits its oncogenic activity by causing immortalization,and to a lesser extent the transformation of cells,in addition to several other mechanisms.The c-MYC proto-oncogene encodes a transcription factor that is critical for cell growth and proliferation.It is one of the genes frequently altered in cancer cells in which it exhibits constitutive activity.Downregulation of c-Myc is critical for 2-Methoxyestradiol(2ME2)-induced oxidative stress and apoptosis in AML cells.And its up-regulation is important for promoting lymphocyte cell division,and demonstrating that GFP-c-Myc expression is a marker of proliferating lymphocytes in vivo. |
| Uniprot ID | P01106 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100ICC/IF Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 Immunocoprecipitation 1:20 Flow cytometry (FCM) 1:20 |
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